J Pharm Sci. 2013 Jul;102(7):2120-7. Inhibitory effects of hesperetin derivatives on guinea pig phosphodiesterases and their ratios between high- and low-affinity rolipram binding.[Pubmed: 23666855] The phosphodiesterase (PDE)4 molecule exists as two distinct conformers, PDE4H and PDE4L , which have high and low affinities, respectively, for the selective PDE4 inhibitor, rolipram.
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CRC Abbreviation for: calcium release channel Cancer Research Campaign (Medspeak-UK) cerebrovascular reserve capacity Certified Rehabilitation Counselor Clinical Research Centre (Medspeak-UK) colorectal cancer (Medspeak-UK) concentration-response curve contraction-relaxation cycle creatinine clearance cancer (kan'ser) [L. cancer, crab, suppurating ulcer
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